ea0090rc4.4 | Rapid Communications 4: Reproductive and Developmental Endocrinology | ECE2023
Tatiana Lecot-Connan
, Yasmine Boumerdassi
, Francoise Magnin
, Nadine Binart
, Charlotte Sonigo
, Beau Isabelle
Background: The reserve pool of primordial follicles (PMF) is finely regulated by molecules implicated in follicular growth or PMF survival. Anti-Müllerian Hormone (AMH), produced by granulosa cells of growing follicles, is known for its inhibitory role in the initiation of PMF growth. We observed in a recent in vivo study that injection of AMH into mice seemed to induce an activation of autophagy, a cytoplasmic lysosomal-dependent degradation system, which is im...