Searchable abstracts of presentations at key conferences in endocrinology

ea0090rc4.4 | Rapid Communications 4: Reproductive and Developmental Endocrinology | ECE2023

Is AMH a regulator of autophagy in the ovary?

Tatiana Lecot-Connan , Yasmine Boumerdassi , Francoise Magnin , Nadine Binart , Charlotte Sonigo , Beau Isabelle

Background: The reserve pool of primordial follicles (PMF) is finely regulated by molecules implicated in follicular growth or PMF survival. Anti-Müllerian Hormone (AMH), produced by granulosa cells of growing follicles, is known for its inhibitory role in the initiation of PMF growth. We observed in a recent in vivo study that injection of AMH into mice seemed to induce an activation of autophagy, a cytoplasmic lysosomal-dependent degradation system, which is im...